two-spirit

[ too-spir-it ]
/ ˈtuˌspɪr ɪt /

noun

(in some American Indian tribes) a person, especially a biological male, who adopts the gender identity, dress, and social roles traditionally assigned to the opposite sex.
a person who adopts some combination of male and female gender identity, dress, and social roles, or who identifies as gay, lesbian, transgender, etc.
a culturally distinct gender apart from the male and female gender.

OTHER WORDS FROM two-spirit

two-spirit·ed, adjective