histocompatibility antigen


noun Immunology.

any antigen on the surface of tissue or blood cells that provokes the immune response and subsequent rejection when transplanted to an individual of a different antigenic type, thus determining whether the tissues or organs of a donor and recipient are histocompatible.

Origin of histocompatibility antigen

First recorded in 1965–70

British Dictionary definitions for histocompatibility antigen

histocompatibility antigen

noun

a molecule occurring on the surface of tissue cells that can take several different forms. The differences between histocompatibility antigens are inherited and determine organ transplant rejection

Medical definitions for histocompatibility antigen

histocompatibility antigen

n.

Any of various antigens on the surface of cell membranes that serve to identify a cell as self or nonself and are used to determine whether a tissue graft or transfusion will be accepted by a recipient.