grievous

The tactics almost certainly have saved untold thousands of innocents from grievous injury, even death.

The sudden withholding of these supplies was, therefore, a grievous calamity.

By my troth, his ill-report hath done me grievous detriment.

But grievous it is to think that no one said thanks even to her dead body, though she herself was shy and shrank from all thanks.

Yet it had radical and grievous defects, and these, being in its most vital parts, robbed it of half its efficiency.

Here are four distinct predictions; national peculiarity, grievous oppression, universal dispersion and remarkable preservation.